Allow for related Key Events to share information

[jabedini@rti.org]

The new data model must explicitly include the concept of related KEs whereby they share some (but not all) of the same features, which could represent a source of crosstalk between AOPs containing those KEs that is distinct from the sharing of a single KE.

This data model should also facilitate the reuse of this shared information among those related KEs to avoid increasing the burden on KE authors.

[DanV-AOP]

Related to this, the new data model should facilitate the computational identification of "SODA" - same object, different action. For example, estrogen receptor agonism and estrogen receptor antagonism are separate events in the AOP-Wiki, but they represent opposing actions on the same biological object. For many AOP network applications its important to be able to identify these SODAs in a network.

[Julija4CIAO]

Absolutely! And tagging of KEs by appropriate ontology teems should help. More to come on presentation at SKIG on 28 July 2023.